منابع مشابه
Predicting Carcinogenicity
There has been an exponential growth in stress research in recent years in relation to health and employment. The formidable methodological problems confronting both epidemiological and psychobiological studies in this area have been amply demonstrated to oncologists in the difficulty of adequately testing hypotheses about the role of stress in carcinogenesis and disease progression. Some of th...
متن کامل3 Carcinogenicity
The objective genotoxicity assay the methodology of the carcinogenicity and working group was to assess available for predicting and identifying the human carcinogenicity of chemicals that are subject to review and testing under the Toxic Substances Control Act (TSCA), with emphasis on existing chemicals. Specific objectives were to 1) identify existing assays for assessing or predicting the hu...
متن کاملCarcinogenicity of EBDCs.
In 1997 we published an article in EHP on cytogenetic and thyroid hormonal changes in 49 heavily exposed workers applying ethylene bisdithiocarbamate (EBDC) fungicide to tomatoes, based on a collaborative study done by the U.S. National Institute for Occupational Safety and Health and the Institute of Public Health in Mexico (Steenland et al. 1997). EBDCs are a common class of fungicides (e.g.,...
متن کاملThe carcinogenicity of chromium
The carcinogenicity of chromium compounds is reviewed with specific attention to the gaps in knowledge for risk estimation and research needs. The most important problems at present are whether trivalent chromium compounds cause cancer, and whether there is a difference in cancer causing effects between the soluble and the slightly soluble hexavalent compounds in the practical exposure situatio...
متن کاملCarcinogenicity of saccharin.
Saccharin is carcinogenic for the urinary bladder in rats and mice, and most likely is carcinogenic in human beings. The neoplasms of the urinary bladder are malignant and invade and metastasize. Male rats are more susceptible to urinary bladder carcinogenesis than female rats. Rats exposed as fetuses develop neoplasms more readily than rats exposed as weanlings. The lesions in the urinary blad...
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ژورنال
عنوان ژورنال: Toxicologic Pathology
سال: 2010
ISSN: 0192-6233,1533-1601
DOI: 10.1177/0192623309358907